Where is cholecystokinin (CCK) primarily produced?

Cholecystokinin (CCK) is primarily produced in the intestinal mucosa, specifically in the I cells located in the duodenum and jejunum. CCK plays a crucial role in the digestive process by stimulating the gallbladder to contract and release bile into the small intestine, aiding in the emulsification and digestion of fats. Additionally, CCK promotes the secretion of digestive enzymes from the pancreas and slows down gastric emptying, allowing for more efficient nutrient absorption.

The production of CCK in the intestinal mucosa is a response to the presence of fatty acids and amino acids in the duodenum, emphasizing the role of the intestine in regulating digestion. Understanding the primary location of CCK production is essential for grasping its functions and the overall digestive process.