What malformation is often associated with gastroschisis?

Gastroschisis is a congenital defect characterized by an opening in the abdominal wall, allowing the intestines to protrude outside the body. This condition is noted for its association with various gastrointestinal anomalies, the most significant of which is intestinal atresia. Intestinal atresia refers to a condition where a segment of the intestine is absent or obstructed, leading to severe potential complications including obstruction and malabsorption.

The underlying mechanisms that contribute to the occurrence of intestinal atresia in infants with gastroschisis involve vascular disruptions early in fetal development. These can lead to compromised blood flow and subsequent ischemic injury to the developing bowel, resulting in atresia. This relationship is clinically relevant as it poses additional challenges for management after birth, requiring careful assessment of the intestine when addressing the gastroschisis repair.

While other conditions such as herniation, omphalocele, and diaphragmatic hernia represent significant developmental defects, they are not typically linked with gastroschisis in the manner that intestinal atresia is. Thus, the key connection between gastroschisis and intestinal atresia highlights the importance of thorough preoperative evaluation and understanding of associated anomalies in affected patients.