What is the treatment for cholangitis?

The treatment for cholangitis emphasizes a critical and urgent approach due to the condition's potential to rapidly progress to severe illness or sepsis. The correct answer focuses on addressing the infection and any obstruction in the biliary tree.

Fluid resuscitation is essential in managing cholangitis, particularly since patients often present with sepsis and may be volume depleted. Administering IV antibiotics is vital to combat the infection caused by bacteria ascending into the bile ducts, typically from an obstruction like gallstones or strictures. This antibiotic therapy aims to resolve the infection and prevent further complications.

Emergent drainage is also a crucial component of treatment, especially when there is an obstruction causing the cholangitis. This is generally accomplished through procedures such as endoscopic retrograde cholangiopancreatography (ERCP), where the bile duct can be accessed to relieve the obstruction, or percutaneous drainage if endoscopic access is not feasible.

This multifaceted approach of hydration, antibiotic treatment, and immediate intervention to alleviate any obstruction is fundamental in managing cholangitis effectively and preventing further morbidity.