What is the primary treatment for polyps associated with Peutz-Jeghers syndrome?

The primary treatment for polyps associated with Peutz-Jeghers syndrome involves endoscopic removal. Peutz-Jeghers syndrome is characterized by the presence of multiple gastrointestinal hamartomatous polyps, which can lead to complications such as obstruction or bleeding. While the risk of malignancy is not as pronounced compared to other polyposis syndromes, the management often focuses on the removal of symptomatic polyps to prevent complications and monitor for potential malignant transformation.

Endoscopic removal offers several advantages for managing these polyps, as it is a minimally invasive procedure that can effectively address the polyps located in the gastrointestinal tract, particularly in the small intestine and colon. It allows for direct visualization and removal of polyps during the procedure while minimizing recovery time and associated morbidity compared to more invasive surgical options.

In contrast, options like colectomy are more extensive surgical procedures that may be considered in cases of severe dysplasia or multiple adenomatous changes but are not the primary treatment approach for the typical polyps found in Peutz-Jeghers syndrome. Chemotherapy and radiation therapy are more relevant to the treatment of malignancies and not for polyp management in this syndrome, which emphasizes the importance of appropriate surveillance and endoscopic intervention.