What is the percentage risk of developing pancreatitis and cholangioCA from choledochal cysts?

Choledochal cysts are congenital dilations of the bile duct that can lead to several complications, including pancreatitis and cholangiocarcinoma (cholangioCA).

The option stating a 30% risk for pancreatitis reflects the significant association between choledochal cysts and inflammation of the pancreas. This is due to the obstruction of the pancreatic duct or bile duct by the cyst, leading to increased pressure and potential reflux of pancreatic secretions. The chronic irritation and inflammation from these conditions contribute to an elevated risk of pancreatitis over time.

Furthermore, the 10% risk for cholangioCA is also supported by clinical evidence, as patients with choledochal cysts have a predisposition to developing bile duct cancers due to the long-standing inflammation and ductal dilation associated with these cysts. The risk increases with age and the presence of associated abnormalities or features.

Both the percentages provided highlight the serious long-term risks that patients with choledochal cysts face, warranting close monitoring and potentially early surgical intervention to prevent these complications. Understanding these statistics is crucial for surgical and medical professionals who manage patients with choledochal cysts to help mitigate long-term risks.