What are the primary symptoms of cholangitis?

The primary symptoms of cholangitis align closely with the classic presentation known as Charcot's triad, which includes fever, right upper quadrant (RUQ) pain, and jaundice. This triad reflects the biliary tree's infection due to obstruction, typically from gallstones or strictures.

In acute cholangitis, alterations in the patient’s condition can also manifest, especially in severe cases. Hypotension may occur as a result of septic shock stemming from the systemic inflammatory response to the infection. Additionally, mental status changes can arise due to fluctuating blood pressure, sepsis, or electrolyte disturbances resulting from the infection.

Therefore, recognizing the presence of fever, RUQ pain, jaundice, hypotension, and mental status changes as a comprehensive clinical picture enables effective diagnosis and prompts timely intervention. This approach is essential in managing a potentially life-threatening condition, as timely treatment is critical for cholangitis.