How long after splenic artery ligation should platelets be given?

After splenic artery ligation, the management of platelet transfusion is guided primarily by the patient's platelet count and the risk of bleeding. In this context, significant thrombocytopenia can occur after splenectomy or splenic artery ligation due to the spleen's role in platelet sequestration and clearance.

The correct timing for administering platelet transfusions is aligned with the platelet count. Specifically, prophylactic platelet transfusions are recommended to prevent spontaneous bleeding when the platelet count drops below 50,000 cells/mm³. This threshold is particularly important in surgical patients, as lower platelet counts can increase the risk of hemorrhage.

Therefore, giving platelets when the count falls below this threshold ensures that the patient's hemostatic capability is maintained, particularly in the post-operative setting where the risk for bleeding complications is elevated. Monitoring the platelet count and administering transfusions as needed based on this count is critical for optimal patient management in the context of splenic artery ligation.